Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 16.97
Human Site: S846 Identified Species: 24.89
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S846 Q K L L D A E S E D R P K Q C
Chimpanzee Pan troglodytes XP_518055 1227 139177 S839 Q K L L D A E S E D R P K Q C
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S846 Q K L L D A E S E D R P K Q R
Dog Lupus familis XP_549061 1234 139874 S847 Q K L L D A E S E D R P K H R
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S847 Q K L L D A E S E D R P K Q R
Rat Rattus norvegicus Q7M6Z5 1394 158861 L921 S V D Q L Q K L D E Q R K W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 N850 Q K L L D A D N G D R V K Q R
Frog Xenopus laevis Q91784 1226 138905 E848 K L L D A D G E E E M V K R R
Zebra Danio Brachydanio rerio Q58G59 1363 154819 G939 K V L D Q R R G L E D L E G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 E429 D P E G A E S E S D K E N E A
Honey Bee Apis mellifera XP_395595 1064 123475 A703 R K M E E A F A V N K R L K E
Nematode Worm Caenorhab. elegans P46873 699 78760 E344 P K D A L L R E Y Q E E I A R
Sea Urchin Strong. purpuratus P46872 699 78679 N344 N R A K N I K N K A K I N E D
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 Q690 L Q A I N Q R Q K M V L Q R K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 E812 K E V A R L R E E N E L L K N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 V573 G F D L S G D V F S D N E R A
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 6.6 N.A. N.A. 66.6 20 6.6 N.A. 6.6 13.3 6.6 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 33.3 N.A. N.A. 80 40 26.6 N.A. 20 60 6.6 46.6
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 0 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 40 N.A. N.A. 40 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 13 13 44 0 7 0 7 0 0 0 7 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 7 0 19 13 38 7 13 0 7 44 13 0 0 0 7 % D
% Glu: 0 7 7 7 7 7 32 25 44 19 13 13 13 13 13 % E
% Phe: 0 7 0 0 0 0 7 0 7 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 0 7 7 7 7 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 7 0 7 0 0 0 0 0 7 7 0 0 % I
% Lys: 19 50 0 7 0 0 13 0 13 0 19 0 50 13 7 % K
% Leu: 7 7 50 44 13 13 0 7 7 0 0 19 13 0 7 % L
% Met: 0 0 7 0 0 0 0 0 0 7 7 0 0 0 0 % M
% Asn: 7 0 0 0 13 0 0 13 0 13 0 7 13 0 7 % N
% Pro: 7 7 0 0 0 0 0 0 0 0 0 32 0 0 0 % P
% Gln: 38 7 0 7 7 13 0 7 0 7 7 0 7 32 0 % Q
% Arg: 7 7 0 0 7 7 25 0 0 0 38 13 0 19 38 % R
% Ser: 7 0 0 0 7 0 7 32 7 7 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 13 7 0 0 0 0 7 7 0 7 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _